Quantitative analysis of radiation-induced chromosome aberrations.
نویسندگان
چکیده
We review chromosome aberration modeling and its applications, especially to biodosimetry and to characterizing chromosome geometry. Standard results on aberration formation pathways, randomness, dose-response, proximity effects, transmissibility, kinetics, and relations to other radiobiological endpoints are summarized. We also outline recent work on graph-theoretical descriptions of aberrations, Monte-Carlo computer simulations of aberration spectra, software for quantifying aberration complexity, and systematic links of apparently incomplete with complete or truly incomplete aberrations.
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ورودعنوان ژورنال:
- Cytogenetic and genome research
دوره 104 1-4 شماره
صفحات -
تاریخ انتشار 2004